Elden Ring’s 5 Best Items for Handling Status Effects

Navigating the Lands Between in Elden Ring can be brutal—especially when you're hit with debilitating status effects like Poison, Scarlet Rot, or Frostbite. FromSoftware's open-world epic is filled with dangerous enemies and harsh environments that test your endurance, but the game also provides players with tools to survive these challenges. Having the right Elden Ring items can mean the difference between life and death.

Whether you're exploring a toxic swamp or dueling in PvP, being prepared is essential. Here are five of the best Elden Ring items for handling status effects, based on in-game experience and community-tested reliability.

1. Preserving Boluses

Scarlet Rot is one of the most punishing status effects in Elden Ring. It rapidly drains your health and is commonly encountered in areas like Caelid or Lake of Rot. Preserving Boluses are consumable items that immediately cure Scarlet Rot buildup and active infections. These are indispensable when venturing into rot-heavy zones.

Players looking to stock up on this item can either craft them using the Armorer’s Cookbook [6] or purchase them from select merchants. For players short on time, an Elden Ring items store can be a convenient place to acquire these without farming ingredients or backtracking through dangerous areas.

2. Stanching Boluses

Bleed builds are devastatingly popular in both PvE and PvP. If you’ve ever had your health bar vanish in seconds, you know how dangerous Hemorrhage can be. Stanching Boluses are the perfect response—they reduce bleed buildup and can stop the effect entirely when used at the right time.

This item is particularly useful in PvP scenarios or when facing enemies like the Cleanrot Knights or the Bloodhound Knights. You can find these boluses in the world or buy them from vendors, and they’re also available through various Elden Ring items store options online for players looking to save time.

3. Thawfrost Boluses

Cold and Frostbite effects can not only slow you down but also cause a sudden spike of damage once the status meter fills. Thawfrost Boluses help mitigate this effect and are especially useful in snowy regions like the Consecrated Snowfield or during fights with enemies wielding frost weapons.

These boluses are often underappreciated until you face a frost-inflicting boss. Having a few in your inventory ensures you’re not caught off guard. While they can be crafted, players seeking quick access can look for them through trusted Elden Ring items store vendors.

4. Neutralizing Boluses

Poison is a staple in FromSoftware games, and Elden Ring is no exception. The Neutralizing Boluses remove Poison buildup and cure active poisoning. They're simple, reliable, and an absolute must-have when traversing areas like the Aeonia Swamp.

Their ingredients are relatively easy to find, making them a common part of most players’ item kits. However, for newcomers or speedrunners looking to skip gathering materials, these are readily available in Elden Ring items store inventories.

5. Flame, Cleanse Me (Incantation)

While not a consumable, this Fire-based incantation deserves a spot on the list. Flame, Cleanse Me removes both Poison and Scarlet Rot when cast, offering a reusable solution for players who invest in Faith. It’s a fantastic option for magic-oriented builds or those who want a long-term answer to status effects without consuming boluses.

Pairing this incantation with items like the Preserving Boluses gives you multiple layers of defense, especially when exploring rot-infested dungeons or PvP areas.